Comparison of The Effectiveness of Remifentanyl versus Fentanyl in Pediatric Undergoing Methotrexate Therapy

نویسندگان

چکیده

Background: Anesthesia procedure is routinely performed for some painful pediatric oncologic procedures such as lumbar puncture (LP) and bone marrow examination (BME). Several studies mentioned that fentanyl remifentanyl are often used anesthetic agent of this procedure, but none them compare the recovery time both agent. This study aims to in patients undergoing methoterexate therapy. Subjects Method : was a double-blind randomized controlled trial on 36 who underwent intratechal methotrexate chemoterapy under general anesthesia intervention room Moewardi General Hospital Surakarta met inclusion criteria. The dependent variable independent were remifentanyl. samples divided into 2, Fentanyl (F) Remifentanyl (R) group. Recovery recorded after until subject reached Pediatric Glasgow Comma Scale (PGCS) 15. Statistical analysis Mann Whitney U Test using SPSS 25 Windows. Results mean F group 373.39 ± 29.48 seconds, while R 124.67±11.55 seconds. There significant difference between (p= 0.000). Conclusion: significantly faster than with intrathecal chemotherapy. Keywords: Fentanyl, Methotrexate, Outpatient anesthesia, time, Correspondence: Ferdy Pamungkas. Anesthesiology Department, Hospital, Surakarta. Jalan Kolonel Sutarto 132 Jebres, Kecamatan City 57126. Central Java, Indonesia. [email protected]. +6281230269501. Indonesian Journal Medicine (2022), 07(01): 115-121 https://doi.org/10.26911/theijmed.2022.07.01.12

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ژورنال

عنوان ژورنال: Indonesian journal of medicine

سال: 2022

ISSN: ['2549-0265']

DOI: https://doi.org/10.26911/theijmed.2022.07.01.12